Life Sciences Call 2005 - Molecular Mechanisms and MethodsLS05-039

Molecular Mechanisms of Antivirals


Molecular Mechanisms of Antivirals
Principal Investigator:
Joachim Seipelt
Projekttitel:
Molecular Mechanisms of Antivirals
Status:
Abgeschlossen (01.03.2006 – 31.08.2009) 42 Monate
Fördersumme:
€ 670.100

Kurzzusammenfassung:

The project pursues an interdisciplinary approach to identify the mode of action of three novel antiviral compounds which are effective against picornavirus multiplication, such as human rhinovirus and coxsackievirus. In addition, these substances also inhibit influenza virus, a pathogenic member of the orthomyxoviridae. The molecular basis of the surprising broad antiviral activity of these compounds is not known. We will combine virological and biochemical methods, advanced tools such as proteomics and microarray analysis, animal models, and genome wide screening techniques in yeast to gain insight into the viral and cellular processes targeted by these antiviral compounds. Results from this project will form the basis for development of novel antivirals.

 

Wir nutzen Cookies auf unserer Website. Einige von ihnen sind technisch notwendig, während andere uns helfen, diese Website zu verbessern oder zusätzliche Funktionalitäten zur Verfügung zu stellen. Weitere Informationen